This word I do not particularly like, since it means to empty, an end, “Webster described it as emptying.” An ending can be difficult for some people when they are used to having control. “Their cycle depleted,” if you will. Those habit forming steps to work, school, have to end or deplete at some point, whether through graduation, a promotion/job change, a move, retirement.
It is guaranteed, our lives will “change, several times.” It can be sudden or gradual, that is not known. Once you think you are all set-up somewhere, life suddenly changes. “Just the, “Way It Is.”